Article
Bacillus anthracis comparative genome analysis in support of the Amerithrax investigation.
Proceedings of the National Academy of Sciences of the United States of America - 22 Mar 2011
Rasko David A, Worsham Patricia L, Abshire Terry G, Stanley Scott T, Bannan Jason D, Wilson Mark R, Langham Richard J, Decker R Scott, Jiang Lingxia, Read Timothy D, Phillippy Adam M, Salzberg Steven L, Pop Mihai, Van Ert Matthew N, Kenefic Leo J, Keim Paul S, Fraser-Liggett Claire M, Ravel Jacques
Abstract excerpt
Before the anthrax letter attacks of 2001, the developing field of microbial forensics relied on microbial genotyping schemes based on a small portion of a genome sequence. Amerithrax, the investigation into the anthrax letter attacks, applied high-resolution whole-genome sequencing and comparative genomics to identify key genetic features of the letters' Bacillus anthracis Ames strain. During systematic...
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