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Comparative genomics of Bacillus anthracis A and B-clades reveals genetic variation in genes responsible for spore germination.

Genomics - 1 Sept 2025

Mokgokong Sankwetea P, Hassim Ayesha, Mafuna Tendo, Turner Wendy C, van Heerden Henriette, Lekota Kgaugelo E

Abstract excerpt

Bacillus anthracis, the causative agent of anthrax, is composed of three genetic clades (A, B, and C). Clade-A is the most common and distributed worldwide, B-clade has a narrow geographic distribution, and C-clade is rare. South Africa's Kruger National Park (KNP) has high diversity of B. anthracis, with strains from A and B clades described from its northernmost region, Pafuri. We employed whole genome...

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PMID: 40633701
DOI: 10.1016/j.ygeno.2025.111074

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