Article
Rapid identification of genetic modifications in Bacillus anthracis using whole genome draft sequences generated by 454 pyrosequencing.
PloS one - 25 Aug 2010
Chen Peter E, Willner Kristin M, Butani Amy, Dorsey Shakia, George Matroner, Stewart Andrew, Lentz Shannon M, Cook Christopher E, Akmal Arya, Price Lance B, Keim Paul S, Mateczun Alfred, Brahmbhatt Trupti N, Bishop-Lilly Kimberly A, Zwick Michael E, Read Timothy D, Sozhamannan Shanmuga
Abstract excerpt
BACKGROUND: The anthrax letter attacks of 2001 highlighted the need for rapid identification of biothreat agents not only for epidemiological surveillance of the intentional outbreak but also for implementing appropriate countermeasures, such as antibiotic treatment, in a timely manner to prevent further casualties. It is clear from the 2001 cases that survival may be markedly improved by administration of...
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