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Article

High-throughput sequencing of Bacillus anthracis in France: investigating genome diversity and population structure using whole-genome SNP discovery.

BMC genomics - 16 Apr 2014

Girault Guillaume, Blouin Yann, Vergnaud Gilles, Derzelle Sylviane

Abstract excerpt

BACKGROUND: Single nucleotide polymorphisms (SNPs) are ideal signatures for subtyping monomorphic pathogens such as Bacillus anthracis. Here we report the use of next-generation sequencing technology to investigate the historical, geographic and genetic diversity of Bacillus anthracis in France. 122 strains isolated over a 60-years period throughout the country were whole-genome sequenced and comparative analyses...

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Bacillus anthracis
France
Genome, Bacterial
High-Throughput Nucleotide Sequencing
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Identifiers

PMID: 24734872
DOI: 10.1186/1471-2164-15-288
PMCID: PMC4023602

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