Article
A putative ATP binding protein influences the fidelity of branchpoint recognition in yeast splicing.
Cell - 9 Mar 1990
Burgess S, Couto J R, Guthrie C
Abstract excerpt
We previously described a dominant suppressor of the splicing defect conferred by an A----C intron branchpoint mutation in S. cerevisiae. Suppression occurs by increasing the frequency with which the mutant branchpoint is utilized. We have now cloned the genomic region encoding the prp16-1 suppre...
Topics
- Adenosine Triphosphatases
- Amino Acid Sequence
- Aspartic Acid
- Base Sequence
- Binding Sites
- Chromosome Mapping
- Cloning, Molecular
- Gene Library
- Genes, Dominant
- Genes, Fungal
- Molecular Sequence Data
- Mutation
- Plasmids
- RNA Splicing
- Saccharomyces cerevisiae
- Sequence Homology, Nucleic Acid
- Suppression, Genetic
- Tyrosine