Article
Association between IL28B gene polymorphisms and plasma HCV-RNA levels in HIV/HCV-co-infected patients.
AIDS (London, England) - 27 Mar 2011
Labarga Pablo, Soriano Vincent, Caruz Antonio, Poveda Eva, Di Lello Federico A, Di Lello Frederico, Hernandez-Quero Jose, Moreno Santiago, Bernal Enrique, Miró José M, Leal Manuel, Gutierrez Felix, Portilla Joaquín, Pineda Juan A
Abstract excerpt
BACKGROUND: IL28B polymorphisms influence both the rate of spontaneous hepatitis C virus (HCV) clearance and response to interferon α (IFNα)-based therapy. This observation has been reproduced in HIV-co-infected individuals. Controversy exists about the impact of IL28B alleles on HCV load. METHODS: CoRIS is a nationwide, open cohort of newly diagnosed HIV-1 adults in Spain. In the subset of HCV-co-infected...
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