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Article

Macrophages induce neuroendocrine differentiation of prostate cancer cells via BMP6‐IL6 Loop

3 Mar 2011

Abstract excerpt

BACKGROUND: Frequently associated with hormone refractory prostate cancer are neuroendocrine cells. Because these cells do not express androgen receptors and are castration-resistant, further understanding the mechanism of neuroendocrine differentiation (NED) of prostate cancer cells may yield novel intervention methods in hormone refractory prostate cancer. In this regard, the present study investigated the...

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PMID: 21374653
DOI: 10.1002/pros.21369

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