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Obesity-Modified CD4+ T-Cells Promote an Epithelial-Mesenchymal Transition Phenotype in Prostate Cancer Cells.

Nutrition and cancer - 1 Jan 2022

De Angulo Alejandra, Travis Peyton, Galvan Gloria Cecilia, Jolly Christopher, deGraffenried Linda

Abstract excerpt

Obesity is associated with low-grade chronic inflammation, and metabolic dysregulation. Evidence shows that chronic inflammation inhibits protective immunity mediated by CD4+ T cells. Additionally, obesity-induced inflammation affects prostate cancer progression. However, the effect of obesity on CD4+ T-cell- response to prostate cancer is not well understood. To investigate whether obesity induces changes in...

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PMID: 33715540
DOI: 10.1080/01635581.2021.1898649

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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