Various regulatory sequences are deprived of their uniqueness by the universal rule of TA/CG deficiency and TG/CT excess.

doi:10.1073/pnas.87.3.1218

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Article

Various regulatory sequences are deprived of their uniqueness by the universal rule of TA/CG deficiency and TG/CT excess.

Proceedings of the National Academy of Sciences of the United States of America - 1 Feb 1990

Ohno S, Yomo T

Abstract excerpt

The universal rule of TA/CG deficiency-TG/CT excess endures the extremely high mutation rate of a retrovirus (human immunodeficiency virus type 1) as well as methylation of CAG rather than CG in a plant (maize). Among the consistently abundant nucleotide oligomers, there are two complementary pairs of palindromic nucleotide pentamers containing TG and CA. Out of the CAGTG and CACTG pair emerged the heptameric...

Topics

Animals
Base Composition
Base Sequence
DNA-Binding Proteins
Eulipotyphla
Genes
Genes, Immunoglobulin
Genes, Plant
Genes, Viral
Glucosyltransferases
HIV-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunoglobulin Constant Regions

Immunoglobulin Heavy Chains

Immunoglobulin mu-Chains

Molecular Sequence Data

Mutation

Nucleic Acid Conformation

Regulatory Sequences, Nucleic Acid

Source

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Identifiers

PMID: 2137247
DOI: 10.1073/pnas.87.3.1218
PMCID: PMC53442

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2137247-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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