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Article

Examining the overlap between genome-wide rare variant association signals and linkage peaks in rheumatoid arthritis.

Arthritis and rheumatism - 1 Jun 2011

Eyre S, Ke X, Lawrence R, Bowes J, Panoutsopoulou K, Barton A, Thomson W, Worthington J, Zeggini E

Abstract excerpt

OBJECTIVE: With the exception of the major histocompatibility complex (MHC) and STAT4, no other rheumatoid arthritis (RA) linkage peak has been successfully fine-mapped to date. This apparent failure to identify association under peaks of linkage could be ascribed to the examination of common variation, when linkage is likely to be driven by rare variants. The purpose of this study was to investigate the overlap...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21370227
DOI: 10.1002/art.30315
PMCID: PMC3428937

Genes

STAT4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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