Article
Autosome-wide copy number variation association analysis for rheumatoid arthritis using the WTCCC high-density SNP genotype data.
The Journal of rheumatology - 1 May 2011
Uddin Mohammed, Sturge Mitch, Rahman Proton, Woods Michael O
Abstract excerpt
OBJECTIVE: Rheumatoid arthritis (RA) is a complex autoimmune rheumatic disease that is strongly influenced by genetic factors. Numerous genes are convincingly associated with RA, including genes in tumor necrosis factor signaling (TNF) and the nuclear factor-κB pathway. To date, except for genes within the HLA region, no data exist regarding potential copy number variations (CNV) involving RA-associated genes. We...
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