Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Specific microRNAs are preferentially expressed by skin stem cells to balance self-renewal and early lineage commitment.

Cell stem cell - 4 Mar 2011

Zhang Liang, Stokes Nicole, Polak Lisa, Fuchs Elaine

Abstract excerpt

Increasing evidence suggests that microRNAs may play important roles in regulating self-renewal and differentiation in mammalian stem cells (SCs). Here, we explore this issue in skin. We first characterize microRNA expression profiles of skin SCs versus their committed proliferative progenies and identify a microRNA subset associating with "stemness." Of these, miR-125b is dramatically downregulated in early SC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Cell Lineage
Share to Hair

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Organogenesis

Share to Positive Regulatory Domain I-Binding Factor 1

Share to Receptors, Calcitriol

Share to Stem Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 21362569
DOI: 10.1016/j.stem.2011.01.014
PMCID: PMC3086714

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Specific microRNAs are preferentially expressed by skin stem cells to balance self-renewal and early lineage commitment.PMID 21362569Read ↗

Mir-302 reprograms human skin cancer cells into a pluripotent ES-cell-like stateSemantic proximity Read ↗

Single-Cell RNA Profiling of Human Skin Reveals Age-Related Loss of Dermal Sheath Cells and Their Contribution to a Juvenile PhenotypeSemantic proximity Read ↗

Lef1 expression in fibroblasts maintains developmental potential in adult skin to regenerate woundsSemantic proximity Read ↗

Lef1 expression in fibroblasts maintains developmental potential in adult skin to regenerate woundsSemantic proximity Read ↗

Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian EpidermisSemantic proximity Read ↗

MicroRNA profiling identifies novel regulators of stem cell function in the adult <i>Drosophila</i> intestineSemantic proximity Read ↗

Epigenomic profiling of stem cells within the pilosebaceous unit identifies PRDM16 as a regulator of sebaceous gland homeostasisSemantic proximity Read ↗

MicroRNAs: Modulators of Cell Identity, and their Applications in Tissue EngineeringSemantic proximity Read ↗

The RNA–Methyltransferase Misu (NSun2) Poises Epidermal Stem Cells to DifferentiateSemantic proximity Read ↗

Transcriptional and signalling regulation of skin epithelial stem cells in homeostasis, wounds and cancerSemantic proximity Read ↗

Integrative genome-scale analyses reveal post-transcriptional signatures of early human small intestinal development in a directed differentiation organoid modelSemantic proximity Read ↗

Single-cell transcriptomics reveals spatial and temporal turnover of keratinocyte differentiation regulatorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.