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MicroRNAs: Modulators of Cell Identity, and their Applications in Tissue Engineering

8 Jul 2014

Abstract excerpt

MicroRNAs post-transcriptionally regulate the expression of approximately 60% of the mammalian genes, and have an important role in maintaining the differentiated state of somatic cells through the expression of unique tissuespecific microRNA sets. Likewise, the stemness of pluripotent cells is also sustained by embryonic stem cell-enriched microRNAs, which regulate genes involved in cell cycle, cell signaling...

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PMID: 25069512
DOI: 10.2174/2211536603666140522003539

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