A comprehensive analysis of the COL29A1 gene does not support a role in eczema.

doi:10.1016/j.jaci.2010.12.1123

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Article

A comprehensive analysis of the COL29A1 gene does not support a role in eczema.

The Journal of allergy and clinical immunology - 1 May 2011

Naumann Aline, Söderhäll Cilla, Fölster-Holst Regina, Baurecht Hansjörg, Harde Viola, Müller-Wehling Konstanze, Rodríguez Elke, Ruether Andreas, Franke Andre, Wagenpfeil Stefan, Novak Natalija, Mempel Martin, Kalali Behnam Naderi, Allgaeuer Michael, Koch Jeanette, Gerhard Markus, Melén Erik, Wahlgren Carl-Fredrik, Kull Inger, Stahl Caroline, Pershagen Göran, Lauener Roger, Riedler Josef, Doekes Gert, Scheynius Annika, Illig Thomas, von Mutius Erika, Schreiber Stefan, Kere Juha, Kabesch Michael, Weidinger Stephan

Abstract excerpt

BACKGROUND: Based on a recent positional cloning approach, it was claimed that the collagen 29A1 gene (COL29A1), which encodes an epidermal collagen, represents a major risk gene for eczema underlying a previously reported linkage to chromosome 3q21. However, thus far, not a single replication attempt has been published, and no definitive functional data have been provided. OBJECTIVES: We aimed to determine...

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PMID: 21353297
DOI: 10.1016/j.jaci.2010.12.1123

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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