Article
Variation in genes encoding eosinophil granule proteins in atopic dermatitis patients from Germany.
Journal of negative results in biomedicine - 13 Nov 2008
Parwez Qumar, Stemmler Susanne, Epplen Jörg T, Hoffjan Sabine
Abstract excerpt
BACKGROUND: Atopic dermatitis (AD) is believed to result from complex interactions between genetic and environmental factors. A main feature of AD as well as other allergic disorders is serum and tissue eosinophilia. Human eosinophils contain high amounts of cationic granule proteins, including eosinophil cationic protein (ECP), eosinophil-derived neurotoxin (EDN), eosinophil peroxidase (EPO) and major basic...
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