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Article

Patatin-like phospholipase domain containing 3 sequence variant and hepatocellular carcinoma

25 Feb 2011

Abstract excerpt

In a recent article in HEPATOLOGY, Valenti et al.1 reported an association of the patatin-like phospholipase domain containing 3 (PNPLA3) isoleucine-to-methionine substitution at position 148 (I148M; rs738409) with hepatitis C virus (HCV)-related chronic liver disease. In particular, they showed this genetic variant was associated with fatty liver and fibrosis progression in two independent cohorts of Caucasians...

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PMID: 21351112
DOI: 10.1002/hep.24244

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