Article
Role of fibronectin-binding protein A in Clostridium difficile intestinal colonization.
Journal of medical microbiology - 1 Aug 2011
Barketi-Klai Amira, Hoys Sandra, Lambert-Bordes Sylvie, Collignon Anne, Kansau Imad
Abstract excerpt
Clostridium difficile is a frequent cause of severe, recurrent, post-antibiotic diarrhoea and pseudomembranous colitis. Its pathogenicity is mediated mainly by two toxins, TcdA and TcdB. However, different adhesins have also been described as important colonization factors which are implicated in the first step of the intestinal infection. In this study, we focused our interest on one of these adhesins,...
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