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Article

Surface-layer (S-layer) of human and animal Clostridium difficile strains and their behaviour in adherence to epithelial cells and intestinal colonization.

Journal of medical microbiology - 1 Sept 2013

Spigaglia Patrizia, Barketi-Klai Amira, Collignon Anne, Mastrantonio Paola, Barbanti Fabrizio, Rupnik Maja, Janezic Sandra, Kansau Imad

Abstract excerpt

Clostridium difficile is a frequent cause of severe, recurrent post-antibiotic diarrhoea and pseudomembranous colitis. The surface layer (S-layer) is the predominant outer surface component of C. difficile which is involved in pathogen-host interactions critical to pathogenesis. In this study, we characterized the S-layer protein A (SlpA) of animal and human strains belonging to different PCR-ribotypes (PR) and...

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Identifiers

PMID: 23518658
DOI: 10.1099/jmm.0.056556-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Surface-layer (S-layer) of human and animal Clostridium difficile strains and their behaviour in adherence to epithelial cells and intestinal colonization.PMID 23518658Read ↗

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