Article
Folate and choline metabolism gene variants and development of uterine cervical carcinoma.
Clinical biochemistry - 1 Jun 2011
Mostowska Adrianna, Myka Martyna, Lianeri Margarita, Roszak Andrzej, Jagodziński Pawel P
Abstract excerpt
OBJECTIVE: It has been reported that aberrant DNA methylation can be associated with HPV infection and cervical tumorigenesis. The aim of this study was to evaluate the possibility that polymorphic variants of genes that may affect DNA methylation status are associated with the risk of cervical cancer in the Polish population. DESIGN AND METHOD: Employing PCR-RFLPs and HRM analyses, we examined the prevalence of...
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