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Article

The association between MTHFR polymorphisms and cervical cancer risk: a system review and meta analysis.

Archives of gynecology and obstetrics - 1 Sept 2016

Yi Ke, Yang LingYun, Lan Zhu, Xi MingRong

Abstract excerpt

PURPOSE: Methylenetetrahydrofolate reductase (MTHFR) plays an important role in determining the proportions of folate coenzymes for DNA synthesis or DNA methylation. Published data on the association between the MTHFR polymorphisms and cervical risk are controversial. A meta-analysis was performed to assess whether the polymorphisms of MTHFR are associated with cervical cancer risk. METHODS: Medline, Embase,...

Topics

Female
Genetic Predisposition to Disease
Genotype
Humans
Methylenetetrahydrofolate Reductase (NADPH2)
Polymorphism, Genetic
Publication Bias
Risk Factors
Uterine Cervical Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26879954
DOI: 10.1007/s00404-016-4037-6

Genes

MTHFR

Variants

Provenance

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