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Article

Loss of activator of G-protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jun 2011

Regner Kevin R, Nozu Kandai, Lanier Stephen M, Blumer Joe B, Avner Ellis D, Sweeney William E, Park Frank

Abstract excerpt

The intracellular mechanisms underlying renal tubular epithelial cell proliferation and tubular repair following ischemia-reperfusion injury (IRI) remain poorly understood. In this report, we demonstrate that activator of G-protein signaling 3 (AGS3), an unconventional receptor-independent regulator of heterotrimeric G-protein function, influences renal tubular regeneration following IRI. In rat kidneys exposed...

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Identifiers

PMID: 21343176
DOI: 10.1096/fj.10-169797
PMCID: PMC3101034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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