Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Semaphorin 3A inactivation suppresses ischemia-reperfusion-induced inflammation and acute kidney injury.

American journal of physiology. Renal physiology - 15 Jul 2014

Ranganathan Punithavathi, Jayakumar Calpurnia, Mohamed Riyaz, Weintraub Neal L, Ramesh Ganesan

Abstract excerpt

Recent studies show that guidance molecules that are known to regulate cell migration during development may also play an important role in adult pathophysiologic states. One such molecule, semaphorin3A (sema3A), is highly expressed after acute kidney injury (AKI) in mice and humans, but its pathophysiological role is unknown. Genetic inactivation of sema3A protected mice from ischemia-reperfusion-induced AKI,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Kidney Injury
Share to Apoptosis Regulatory Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cisplatin

Share to Kidney Tubules

Share to Nephritis

Share to Neuropilin-1

Share to Reperfusion Injury

Share to Toll-Like Receptor 4

Source

Open in PubMed Open full text

Identifiers

PMID: 24829504
DOI: 10.1152/ajprenal.00177.2014
PMCID: PMC4101625

Genes

DFFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Semaphorin 3A inactivation suppresses ischemia-reperfusion-induced inflammation and acute kidney injury.PMID 24829504Read ↗

Inhibition of semaphorin-3a suppresses lipopolysaccharide-induced acute kidney injurySemantic proximity Read ↗

Semaphorin 3E regulates apoptosis in the intestinal epithelium during the development of colitisSemantic proximity Read ↗

Semaphorin-4A, an activator for T-cell-mediated immunity, suppresses angiogenesis via Plexin-D1.Semantic proximity Read ↗

Differential endothelial transcriptomics identifies semaphorin 3G as a vascular class 3 semaphorin.Semantic proximity Read ↗

Ablation of proximal tubular suppressor of cytokine signaling 3 enhances tubular cell cycling and modifies macrophage phenotype during acute kidney injury.Semantic proximity Read ↗

Semaphorin 3ASemantic proximity Read ↗

IL-4/IL-13-mediated polarization of renal macrophages/dendritic cells to an M2a phenotype is essential for recovery from acute kidney injury.Semantic proximity Read ↗

Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migrationSemantic proximity Read ↗

Sema3A promotes the resolution of cardiac inflammation after myocardial infarction.Semantic proximity Read ↗

Chemorepellent Semaphorin 3E Negatively Regulates Neutrophil Migration In Vitro and In VivoSemantic proximity Read ↗

Autocrine class 3 semaphorin system regulates slit diaphragm proteins and podocyte survivalSemantic proximity Read ↗

Endothelial Semaphorin 7A promotes inflammation in seawater aspiration-induced acute lung injury.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.