Article
Mediator and post-recruitment regulation of RNA polymerase II.
Transcription - 1 Jan 2000
Knuesel Matthew T, Taatjes Dylan J
Abstract excerpt
The human Mediator complex interacts extensively with the RNA polymerase II (Pol II) enzyme and recent data from our lab suggest activator-induced structural shifts within Mediator trigger activation of stalled Pol II. These results are discussed together with other recent findings regarding post-recruitment regulation of Pol II.
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