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Article

Single nucleotide polymorphisms in tobacco metabolism and DNA repair genes and prognosis in resected non-small-cell lung cancer.

The Journal of surgical research - 1 May 2011

Campayo Marc, Viñolas Nuria, Navarro Alfons, Carcereny Enric, Casas Francesc, Gel Bernat, Diaz Tania, Gimferrer Josep Maria, Marrades Ramon M, Ramirez Jose, Monzo Mariano

Abstract excerpt

BACKGROUND: If tobacco-related carcinogens are not inactivated or extruded from the cell, they can damage the DNA. Single nucleotide polymorphisms (SNPs) in genes involved in tobacco metabolism, DNA repair, and multidrug resistance have been related to lung cancer susceptibility. We examined 13 SNPs in 10 of these genes and correlated the results with time to progression (TTP) and overall survival (OS) in 71...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21324488
DOI: 10.1016/j.jss.2011.01.007

Genes

XPC
ERCC1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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