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Article

Outcome of children treated with haematopoietic-stem cell transplantations from donors expressing the rare C77G variant of the PTPRC (CD45) gene.

British journal of haematology - 1 Apr 2011

Samaan Samaan, Guérin-El Khourouj Valérie, Auboeuf Didier, Peltier Lucas, Pédron Béatrice, Ouachée-Chardin Marie, Gourgouillon Nadége, Baruchel André, Dalle Jean-Hugues, Sterkers Ghislaine

Abstract excerpt

The uncommon C77G polymorphism of the Protein-Tyrosine Phosphatase (PTPRC) gene (PTPRC; previously termed CD45) could confer an increased risk of immunopathology. This study compared the outcome of children following human leucocyte antigen-matched unrelated haematopoïetic-stem cell transplantations (HSCT) from donors carrying (C77G cases: n = 8) or not (controls: n = 36) the PTPRC C77G polymorphism. Transmission...

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Source

Identifiers

PMID: 21323873
DOI: 10.1111/j.1365-2141.2011.08568.x

Genes

PTPRC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Outcome of children treated with haematopoietic-stem cell transplantations from donors expressing the rare C77G variant of the PTPRC (CD45) gene.PMID 21323873Read ↗

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