Effect of donor STAT4 polymorphism rs7574865 on clinical outcomes of pediatric acute leukemia patients after hematopoietic stem cell transplant.

doi:10.1016/j.intimp.2016.12.007

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Article

Effect of donor STAT4 polymorphism rs7574865 on clinical outcomes of pediatric acute leukemia patients after hematopoietic stem cell transplant.

International immunopharmacology - 1 Feb 2017

Wun Cheng Mun, Piao Zhe, Hong Kyung Taek, Choi Jung Yoon, Hong Che Ry, Park June Dong, Park Kyung Duk, Shin Hee Young, Kang Hyoung Jin

Abstract excerpt

STAT4 polymorphism, rs7574865 is linked to various autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis. Its T minor allele is associated with higher STAT4 mRNA and protein expression, indicating a stronger skewed immune response than the norm. Although widely studied in autoimmune disease patients and the general population, its effect on immunocompromised subjects is still unknown....

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PMID: 27960128
DOI: 10.1016/j.intimp.2016.12.007

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STAT4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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