Article
Expression patterns of prion protein gene in differential genotypes sheep: quantification using molecular beacon real-time RT-PCR.
Virus genes - 1 Jun 2011
Wang Chuan, Wu Run, Li Fa-Di, Liu Lei, Zhang Xiao-Li, Zhao Chun-Lin, Diao Xiao-Long, Guan Hong-Wei
Abstract excerpt
Determination of the transcription level of cellular prion protein (PrP(C)) is essential for understanding its role in organisms and revealing mechanism of susceptibility and resistance to scrapie. However, the expression of prion protein (PrP) mRNA in sheep has not been quantified in great detail in digestive tract which is important during scrapie spread through oral route. Herein, we report on measurement of...
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