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Article

Post-mortem ABCB1 genotyping reveals an elevated toxicity for female digoxin users.

International journal of legal medicine - 1 Mar 2011

Neuvonen Anu M, Palo Jukka U, Sajantila Antti

Abstract excerpt

BACKGROUND: P-glycoprotein, a common transporter molecule, is known to affect metabolic functions in humans. Polymorphisms of the multidrug resistance gene (ABCB1/MDR1) coding for P-glycoprotein have been linked to changes in the processing of several commonly used medications in patients. Here, we have evaluated the impact of ABCB1 single nucleotide polymorphisms on digoxin fatality, through investigation of the...

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Source

Identifiers

PMID: 21311904
DOI: 10.1007/s00414-011-0550-0

Genes

ABCB1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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