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Article

RET-protooncogene variants in patients with sporadic neoplasms of the digestive tract and the central nervous system.

International journal of colorectal disease - 1 Jul 2011

Rückert Felix, Görgens Heike, Richter Ines, Krex Dietmar, Schackert Gabriele, Kuhlisch Eberhard, Fitze Guido, Saeger Hans-Detlev, Pilarsky Christian, Grützmann Robert, Schackert Hans K

Abstract excerpt

PURPOSE: The RET protooncogene plays a crucial role in neural crest development; accordingly, mutations of RET cause MEN2A and familial medullary thyroid carcinoma, while the expression deregulation of RET is involved in the pathophysiology of glioblastoma multiforme (GBM) and pancreatic cancer (PDAC). The aim of this study was to evaluate if germline variants of the RET protooncogene are associated with GBM,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21311890
DOI: 10.1007/s00384-011-1150-7

Genes

RET

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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