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Article

Drosophila Acyl-CoA synthetase long-chain family member 4 regulates axonal transport of synaptic vesicles and is required for synaptic development and transmission.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 9 Feb 2011

Liu Zhihua, Huang Yan, Zhang Yi, Chen Di, Zhang Yong Q

Abstract excerpt

Acyl-CoA synthetase long-chain family member 4 (ACSL4) converts long-chain fatty acids to acyl-CoAs that are indispensable for lipid metabolism and cell signaling. Mutations in ACSL4 cause nonsyndromic X-linked mental retardation. We previously demonstrated that Drosophila dAcsl is functionally homologous to human ACSL4, and is required for axonal targeting in the brain. Here, we report that Drosophila dAcsl...

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Identifiers

PMID: 21307243
DOI: 10.1523/JNEUROSCI.3278-10.2011
PMCID: PMC6633061

Genes

ACSL4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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