Article
Modeling recent positive selection using identity-by-descent segments.
American journal of human genetics - 7 Nov 2024
Temple Seth D, Waples Ryan K, Browning Sharon R
Abstract excerpt
Recent positive selection can result in an excess of long identity-by-descent (IBD) haplotype segments overlapping a locus. The statistical methods that we propose here address three major objectives in studying selective sweeps: scanning for regions of interest, identifying possible sweeping alleles, and estimating a selection coefficient s. First, we implement a selection scan to locate regions with excess IBD...
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