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Article

The UFM1 conjugation system in mammalian development

18 Mar 2023

Abstract excerpt

Posttranslational modifications by ubiquitin and ubiquitin-like proteins are important in regulating cellular protein functions. UFM1 (ubiquitin-fold modifier 1), first identified almost two decades ago, is a member of the ubiquitin-like protein family. UFM1 is covalently conjugated to the target proteins in an enzymatic cascade consisting of E1 (activating), E2 (conjugating), and E3 (ligating) enzymes. At the...

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PMID: 36932998
DOI: 10.1002/dvdy.586

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