Article
Genome-based analysis of the nonhuman primate Macaca fascicularis as a model for drug safety assessment.
Genome research - 1 Oct 2011
Ebeling Martin, Küng Erich, See Angela, Broger Clemens, Steiner Guido, Berrera Marco, Heckel Tobias, Iniguez Leonardo, Albert Thomas, Schmucki Roland, Biller Hermann, Singer Thomas, Certa Ulrich
Abstract excerpt
The long-tailed macaque, also referred to as cynomolgus monkey (Macaca fascicularis), is one of the most important nonhuman primate animal models in basic and applied biomedical research. To improve the predictive power of primate experiments for humans, we determined the genome sequence of a Macaca fascicularis female of Mauritian origin using a whole-genome shotgun sequencing approach. We applied a template...
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