Article
Inherited balanced translocation t(9;17)(q33.2;q25.3) concomitant with a 16p13.1 duplication in a patient with schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Mar 2011
Fullston Tod, Gabb Bronte, Callen David, Ullmann Reinhard, Woollatt Erica, Bain Sharon, Ropers Hilger H, Cooper Matt, Chandler David, Carter Kim, Jablensky Assen, Kalaydjieva Luba, Gecz Jozef
Abstract excerpt
We report two rare genetic aberrations in a schizophrenia patient that may act together to confer disease susceptibility. A previously unreported balanced t(9;17)(q33.2;q25.3) translocation was observed in two schizophrenia-affected members of a small family with diverse psychiatric disorders. The proband also carried a 1.5 Mbp microduplication at 16p13.1 that could not be investigated in other family members....
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