Article
[Frequencies distribution of human leukocyte antigen-B27 subtypes in healthy Chinese].
Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae - 1 Apr 2006
Yang Guang, Deng Ya-jun, Yan Chun-xia, Wu Dong-ying, Hu Song-nian, Zhu Bo-feng, Li Sheng-bin, Zhang Xiu-qing, Liu Yao
Abstract excerpt
OBJECTIVE: To investigate the frequencies distribution of human leukocyte antigen (HLA)-B27 subtypes in unrelated healthy Chinese. METHOD: Polymerase chain reaction sequence-based typing (PCRSBT) was used to determine HLA high-resolution genotypes of 825 unrelated healthy Chinese. RESULTS: A total of 25 HLA-B27-positive individuals and 8 HLA-B27 subtypes were detected. These subtypes and their corresponding...
Topics
- Adult
- Asian People
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- HLA-B27 Antigen
- Humans
- Male
- Polymerase Chain Reaction
- Sequence Analysis, DNA
- Spondylitis, Ankylosing
