Article
[Clinical outcomes of lamivudine therapy and HLA alleles in chronic hepatitis B patients].
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi - 1 Dec 2008
Oh Ji Min, Kwon Kyu Heum, Kim Jang Eon, Choi Jin Ho, Beom Sun Hee, Lee Sang Hyuk, Lee Yong Jik, Park Mi Young, Jung Mee Kyung, Lee Kye Heui
Abstract excerpt
BACKGROUND/AIMS: The human leukocyte antigen (HLA) system is an integral component of immune response. Highly polymorphic HLA genes may play a pivotal role in the response of antiviral therapy. We investigated the effects of HLA gene polymorphism on the clinical outcome of chronic hepatitis B patients who received lamivudine treatment. METHODS: Depending on their clinical response to lamivudine therapy, a total...
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