Article
[Ankylosing spondylitis and heterogenity of HLA-B27 in Chinese].
Zhonghua wai ke za zhi [Chinese journal of surgery] - 1 Jun 1996
Lin J, Lu H, Feng C
Abstract excerpt
HLA-B27 represents a family of closely related antigens. More than six alleles differing in limited number of nucleotide substitution had been described (B2701-B2706). We subtyped HLA-B27 in 76 patients with ankylosing spondylitis (AS) and 1200 Chinese healthy persons of Han nationality. Polymerase chain reaction was designed to amplify specific regions for class I (exon 2 and 3). Amplified sequences were tested...
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