Article
[Spondylarthritis ankylopoietica and HLA-B27].
Terapevticheskii arkhiv - 1 Jan 1992
Benevolenskaia L I
Abstract excerpt
There is a strict association between HLA-B27 and a group of spondylarthropathies, especially with ankylosing spondylarthritis (AS). The causes of the association remain obscure, different hypotheses are regarded. There is an interaction between B27 and bacteria. However, the etiological and pathogenetic roles played by any of them in AS cannot be regarded as proved. B27 is an important genetic factor in the...
Topics
- Alleles
- Genes, Dominant
- Genes, MHC Class I
- HLA-B27 Antigen
- Humans
- Spondylitis, Ankylosing