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Article

Identification of metabolic modifiers that underlie phenotypic variations in energy-balance regulation.

Diabetes - 1 Mar 2011

Chang Chia Lin, Cai James J, Cheng Po Jen, Chueh Ho Yen, Hsu Sheau Yu Teddy

Abstract excerpt

OBJECTIVE: Although recent studies have shown that human genomes contain hundreds of loci that exhibit signatures of positive selection, variants that are associated with adaptation in energy-balance regulation remain elusive. We reasoned that the difficulty in identifying such variants could be due to heterogeneity in selection pressure and that an integrative approach that incorporated experiment-based evidence...

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Identifiers

PMID: 21300845
DOI: 10.2337/db10-1331
PMCID: PMC3046833

Genes

GIP
GIPR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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