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Article

Genetic variants in TLR2 and TLR4 are associated with markers of monocyte activation: the Atherosclerosis Risk in Communities MRI Study.

Human genetics - 1 Jun 2011

Bielinski Suzette J, Hall Jennifer L, Pankow James S, Boerwinkle Eric, Matijevic-Aleksic Nena, He Max, Chambless Lloyd, Folsom Aaron R

Abstract excerpt

Markers of monocyte activation play a critical role in atherosclerosis, but little is known about the genetic influences on cellular levels. Therefore, we investigated the influence of genetic variants in monocyte differentiation antigen (CD14), toll-like receptor-4 (TLR4), toll-like receptor-2 (TLR2), and myeloperoxidase (MPO) on monocyte surface receptor levels. The study sample consisted of 1,817 members of a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21298446
DOI: 10.1007/s00439-011-0962-4
PMCID: PMC3417332

Genes

TLR2
TLR4
MPO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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