Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Predictions in the face of clinical reality: HistoCheck versus high-risk HLA allele mismatch combinations responsible for severe acute graft-versus-host disease.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Sept 2011

Askar Medhat, Sobecks Ronald, Morishima Yasuo, Kawase Takakazu, Nowacki Amy, Makishima Hideki, Maciejewski Jaroslaw

Abstract excerpt

HLA polymorphism remains a major hurdle for hematopoietic stem cell transplantation (HSCT). In 2004, Elsner et al. proposed the HistoCheck Web-based tool to estimate the allogeneic potential between HLA-mismatched stem cell donor/recipient pairs expressed as a sequence similarity matching (SSM). SSM is based on the structure of HLA molecules and the functional similarity of amino acids. According to this...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Disease
Share to Algorithms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Amino Acid Sequence

Share to Graft vs Host Disease

Share to Histocompatibility

Share to HLA Antigens

Share to Predictive Value of Tests

Share to Severity of Illness Index

Source

Identifiers

PMID: 21296176
DOI: 10.1016/j.bbmt.2011.01.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Predictions in the face of clinical reality: HistoCheck versus high-risk HLA allele mismatch combinations responsible for severe acute graft-versus-host disease.PMID 21296176Read ↗

Scoring HLA class I mismatches by HistoCheck does not predict clinical outcome in unrelated hematopoietic stem cell transplantation.Semantic proximity Read ↗

Three-dimensional structure discrepancy between HLA alleles for effective prediction of aGVHD severity and optimal selection of recipient-donor pairs: a proof-of-concept study.Semantic proximity Read ↗

An approach to predicting hematopoietic stem cell transplantation outcome using HLA-mismatch information mapped on protein structure data.Semantic proximity Read ↗

Hidden genomic MHC disparity between HLA-matched sibling pairs in hematopoietic stem cell transplantation.Semantic proximity Read ↗

High-resolution HLA matching in hematopoietic stem cell transplantation: a retrospective collaborative analysisSemantic proximity Read ↗

Landscapes of HLA Mismatching in Contemporary Unrelated Haematopoietic Cell Transplantation.Semantic proximity Read ↗

Role of HLA in hematopoietic SCT.Semantic proximity Read ↗

High-risk HLA allele mismatch combinations responsible for severe acute graft-versus-host disease and implication for its molecular mechanism.Semantic proximity Read ↗

The Immunogenicity of HLA Class II Mismatches: The Predicted Presentation of Nonself Allo-HLA-Derived Peptide by the HLA-DR Phenotype of the Recipient Is Associated with the Formation of DSA.Semantic proximity Read ↗

Refined HLA-DPB1 mismatch with molecular algorithms predicts outcomes in hematopoietic stem cell transplantationSemantic proximity Read ↗

Matchmaker, matchmaker make me a match: Opportunities and challenges in optimizing compatibility of HLA eplets in transplantation.Semantic proximity Read ↗

PIRCHE-II Risk and Acceptable Mismatch Profile Analysis in Solid Organ Transplantation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.