Article
Calcium/NFAT signalling promotes early nephrogenesis.
Developmental biology - 15 Apr 2011
Burn S F, Webb A, Berry R L, Davies J A, Ferrer-Vaquer A, Hadjantonakis A K, Hastie N D, Hohenstein P
Abstract excerpt
A number of Wnt genes are expressed during, and are known to be essential for, early kidney development. It is typically assumed that their products will act through the canonical β-catenin signalling pathway. We have found evidence that suggests canonical Wnt signalling is not active in the early nephrogenic metanephric mesenchyme, but instead provide expressional and functional evidence that implicates the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
