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Article

NFATc1 identifies a population of proximal tubule cell progenitors.

Journal of the American Society of Nephrology : JASN - 1 Feb 2009

Langworthy Melissa, Zhou Bin, de Caestecker Mark, Moeckel Gilbert, Baldwin H Scott

Abstract excerpt

Recovery from acute kidney injury requires regeneration of tubule cells. Because calcineurin induces nuclear transport of NFATc proteins, whose expression pattern correlates with the nephron segments injured by calcineurin inhibitors, we hypothesized that NFATc1 plays a role in modifying epithelial regeneration after injury. To test this, we induced proximal tubular cell (PTC) injury in Balb/c mice and...

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Identifiers

PMID: 19118153
DOI: 10.1681/ASN.2008010094
PMCID: PMC2637056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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