Article
Evaluation of four novel genetic variants affecting hemoglobin A1c levels in a population-based type 2 diabetes cohort (the HUNT2 study).
BMC medical genetics - 4 Feb 2011
Hertel Jens K, Johansson Stefan, Ræder Helge, Platou Carl G P, Midthjell Kristian, Hveem Kristian, Molven Anders, Njølstad Pål R
Abstract excerpt
BACKGROUND: Chronic hyperglycemia confers increased risk for long-term diabetes-associated complications and repeated hemoglobin A1c (HbA1c) measures are a widely used marker for glycemic control in diabetes treatment and follow-up. A recent genome-wide association study revealed four genetic loci, which were associated with HbA1c levels in adults with type 1 diabetes. We aimed to evaluate the effect of these...
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