Article
Impact of Genetic Determinants of HbA1c on Type 2 Diabetes Risk and Diagnosis.
Current diabetes reports - 21 Jun 2018
Sarnowski Chloé, Hivert Marie-France
Abstract excerpt
PURPOSE OF REVIEW: Glycated hemoglobin (A1c) is used to diagnose type 2 diabetes and monitor glycemic control. Specific genetic variants interfere with A1c and effects/frequencies of some variants vary by ancestry. In this review, we summarize findings from large trans-ethnic meta-analyses of genome-wide association studies (GWAS) of A1c and describe some variants influencing erythrocyte biology and interfering...
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