Article
Studies of a genetic variant in HK1 in relation to quantitative metabolic traits and to the prevalence of type 2 diabetes.
BMC medical genetics - 25 Jul 2011
Gjesing Anette P, Nielsen Aneta A, Brandslund Ivan, Christensen Cramer, Sandbæk Anneli, Jørgensen Torben, Witte Daniel, Bonnefond Amélie, Froguel Phillippe, Hansen Torben, Pedersen Oluf
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) within the gene encoding Hexokinase 1 (HK1) are associated with changes in glycated haemoglobin (HbA1c) levels. Our aim was to investigate the effect of HK1 rs7072268 on measures of glucose- and lipid-metabolism in a Danish non-diabetic population and combine the outcome of these analyses in a meta-analysis with previously published results. Furthermore, our aim...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.