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Article

Requirement for period gene expression in the adult and not during development for locomotor activity rhythms of imaginal Drosophila melanogaster.

Journal of neurogenetics - 1 Nov 1990

Ewer J, Hamblen-Coyle M, Rosbash M, Hall J C

Abstract excerpt

Mutations at the period (per) locus of Drosophila melanogaster disrupt the circadian rhythm of adult locomotor activity. Molecular studies have shown that this gene is expressed primarily at the embryonic, pupal and adult stages. We have used conditional per mutants to infer the stages of development during which per expression is required for adult rhythmicity. In experiments carried out with germline...

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PMID: 2129172
DOI: 10.3109/01677069009084151

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Requirement for period gene expression in the adult and not during development for locomotor activity rhythms of imaginal Drosophila melanogaster.PMID 2129172Read ↗

The strength and periodicity of D. melanogaster circadian rhythms are differentially affected by alterations in period gene expression.Semantic proximity Read ↗

Molecular and behavioral analysis of four period mutants in Drosophila melanogaster encompassing extreme short, novel long, and unorthodox arrhythmic types.Semantic proximity Read ↗

New short period mutations of the Drosophila clock gene per.Semantic proximity Read ↗

Changes in abundance or structure of the per gene product can alter periodicity of the Drosophila clock.Semantic proximity Read ↗

Circadian fluctuations of period protein immunoreactivity in the CNS and the visual system of Drosophila.Semantic proximity Read ↗

Cis-combination of the classic per(S) and per(L) mutations results in arrhythmic Drosophila with ectopic accumulation of hyperphosphorylated PERIOD protein.Semantic proximity Read ↗

Expression of the period clock gene within different cell types in the brain of Drosophila adults and mosaic analysis of these cells' influence on circadian behavioral rhythms.Semantic proximity Read ↗

The analysis of new short-period circadian rhythm mutants suggests features of D. melanogaster period gene function.Semantic proximity Read ↗

Robust circadian rhythmicity of Per1 and Per2 mutant mice in constant light, and dynamics of Per1 and Per2 gene expression under long and short photoperiods.Semantic proximity Read ↗

Involvement of the period gene in developmental time-memory: effect of the perShort mutation on phase shifts induced by light pulses delivered to Drosophila larvae.Semantic proximity Read ↗

Constitutive expression of the <i>Period1</i> gene impairs behavioral and molecular circadian rhythmsSemantic proximity Read ↗

Cooperative interaction between phosphorylation sites on PERIOD maintains circadian period in Drosophila.Semantic proximity Read ↗

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