Article
Requirement for period gene expression in the adult and not during development for locomotor activity rhythms of imaginal Drosophila melanogaster.
Journal of neurogenetics - 1 Nov 1990
Ewer J, Hamblen-Coyle M, Rosbash M, Hall J C
Abstract excerpt
Mutations at the period (per) locus of Drosophila melanogaster disrupt the circadian rhythm of adult locomotor activity. Molecular studies have shown that this gene is expressed primarily at the embryonic, pupal and adult stages. We have used conditional per mutants to infer the stages of develop...
Topics
- Activity Cycles
- Alleles
- Animals
- Blotting, Northern
- Circadian Rhythm
- Drosophila Proteins
- Drosophila melanogaster
- Gene Expression
- Genotype
- Heat-Shock Proteins
- Immunohistochemistry
- Motor Activity
- Mutation
- Nuclear Proteins
- Period Circadian Proteins
- Phenotype
- Proteins
- Recombinant Fusion Proteins