Article
Modulation of the malignant phenotype with the urokinase-type plasminogen activator and the type I plasminogen activator inhibitor.
Cell differentiation and development : the official journal of the International Society of Developmental Biologists - 2 Dec 1990
Sordat B, Reiter L, Cajot J F
Abstract excerpt
Gene transfer techniques were utilized to evaluate the role of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (PAI-1) in enhancing or preventing the expression of the invasive malignant phenotype, respectively. Mouse L-cell transfectants expressing human uPA or human PAI-1 as well as mouse B16 transfectants expressing mouse uPA or human PAI-1 were generated. These...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
