Modulation of the malignant phenotype with the urokinase-type plasminogen activator and the type I plasminogen activator inhibitor.

doi:10.1016/0922-3371(90)90040-4

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Article

Modulation of the malignant phenotype with the urokinase-type plasminogen activator and the type I plasminogen activator inhibitor.

Cell differentiation and development : the official journal of the International Society of Developmental Biologists - 2 Dec 1990

Sordat B, Reiter L, Cajot J F

Abstract excerpt

Gene transfer techniques were utilized to evaluate the role of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (PAI-1) in enhancing or preventing the expression of the invasive malignant phenotype, respectively. Mouse L-cell transfectants expressing human uPA...

Topics

Animals
Colonic Neoplasms
Extracellular Matrix
Extracellular Matrix Proteins
Heat-Shock Proteins
Hot Temperature
Humans
L Cells
Lung Neoplasms
Melanoma, Experimental
Mice
Mice, Inbred C57BL
Neoplasm Invasiveness
Neoplasm Metastasis
Neoplasm Transplantation
Phenotype
Plasminogen Activators
Plasminogen Inactivators

Source

Open in PubMed

Identifiers

PMID: 2129155
DOI: 10.1016/0922-3371(90)90040-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2129155-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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