Article
Decreased expression of intercellular adhesion molecule-1 (ICAM-1) and urokinase-type plasminogen activator receptor (uPAR) is associated with tumor cell spreading in vivo.
Clinical & experimental metastasis - 1 Jan 2002
Donadio Ana C, Remedi María M, Frede Silvia, Bonacci Gustavo R, Chiabrando Gustavo A, Pistoresi-Palencia María C
Abstract excerpt
The development of an effective antitumor immune response to control tumor growth is influenced by the tumor cell itself and/or by the tumor microenvironment. Tumor invasion and tumor cell spreading require a finely tuned regulation of the formation and loosening of adhesive contacts of tumor cells with the extracellular matrix (ECM). In our laboratory, a rat tumor cell line derived from a spontaneous rat sarcoma...
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