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Article

Functional effects of genetic polymorphisms in the N-acetyltransferase 1 coding and 3' untranslated regions.

Birth defects research. Part A, Clinical and molecular teratology - 1 Feb 2011

Zhu Yuanqi, States J Christopher, Wang Yang, Hein David W

Abstract excerpt

BACKGROUND: The functional effects of N-acetyltransferase 1 (NAT1) polymorphisms and haplotypes are poorly understood, compromising the validity of associations reported with diseases, including birth defects and numerous cancers. METHODS: We investigated the effects of genetic polymorphisms within the NAT1 coding region and the 3'-untranslated region (3'-UTR) and their associated haplotypes on N- and...

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Source

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Identifiers

PMID: 21290563
DOI: 10.1002/bdra.20763
PMCID: PMC3252750

Genes

NAT1

Variants

rs4987076
rs4987076

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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